Bisoprolol is a commonly prescribed medication in the treatment of high blood pressure. The use of this medication should be as directed to achieve the best blood pressure control effect.

What drug is Bisotexa?

Bisotexa contains the active ingredient Bisoprolol fumarate belongs to the group of beta-blockers (beta blockers) that have a selective effect on beta-1 receptors in the heart, inhibiting these receptors, thereby reducing the heart rate and reducing myocardial demand for oxygen. 

The drug is indicated for the treatment of:

- Hypertension.

- Stable chronic angina.

- Stable chronic heart failure with impaired left ventricular systolic function has been treated along with ACE inhibitors, diuretics, and cardiac glycosides.

The drug is contraindicated in the presence of pathologies:

- Atrioventricular block of the second or third degree.

- Acute heart failure and uncontrolled heart failure.

- Bradycardia, sinus node disease with fainting, dizziness.

- Asthma, chronic obstructive pulmonary disease or respiratory disease because bisoprolol can aggravate bronchospasm, worsen shortness of breath.

- Adrenal myeloma.

- Hypersensitivity to bisoprolol.

What dosage forms and in what content does Bisotexa have?

Bisotexa drug contains the active ingredient Bisoprolol fumarate available in the form of tablets with the following contents: Bisoprolol 2.5mg, Bisoprolol 5mg, Bisoprolol 10mg.

Bisoprolol instructions for safe and effective use

To maximize the effectiveness of the treatment of arrhythmias of the drug, limiting adverse effects, you need to use the drug correctly and note the following:

- How to use, when to take the drug

Bisoprolol is administered orally. Because food does not affect the absorption of the drug, patients can take it before or after meals as directed by the doctor. However, do not use Bisoprolol with grapefruit juice because grapefruit juice may affect drug metabolism in the body. In addition, you should also take the medicine at a certain time frame such as the morning to create a habit of taking the medicine on time. 

- Drug dosage

Depending on the medication and different types of arrhythmias and the health condition of the patient, doctors will prescribe the most appropriate dosage. The initial dose of bisoprolol is 2.5mg/day. If arrhythmias, heart palpitations, palpitations, angina are not improved, and the tolerability of the drug in patients is low, it will be necessary to consider increasing the dose. Patients will be gradually increased dose to a maximum of 20mg / day.

- Handling when the dose is missed

If you forget to take Bisoprolol, take it as soon as you remember if the forgetfulness time is less than 12 hours. If you have missed your dose for more than 12 hours, you should skip that dose and take the next dose, never double the dose.

Other notes when taking the drug

When taking Bisoprolol drugs to treat arrhythmias, patients should also pay additional attention to the following notes:

- Do not stop the drug abruptly

- Regular health monitoring is required during medication

- Tell your doctor about any medications you are currently taking  

This will help the doctor consider appropriate indications, avoiding the risk of interaction of bisoprolol drugs with some other groups of drugs such as antiarrhythmic drugs, clonidine, diabetes drugs, anesthetics, digitalis, analgesics and anti-inflammatories, sympathomimetic drugs, epileptic drugs, psychotropic,  rifampicin...

Link:
https://www.medicalnewstoday.com/articles/bisoprolol-oral-tablet
https://www.webmd.com/drugs/2/drug-14206/bisoprolol-fumarate-oral/details/list-contraindications

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